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Biomolecular acoustic sensors

Ultrasound imaging of acoustic biomolecules

Transcranial ultrasound imaging of neural activity

The recent introduction of genetically encoded biomolecules as ultrasound contrast agents is opening new opportunities for deep molecular imaging in opaque organisms. We engineer biosensors based on these acoustic biomolecules to spy on cellular processes with ultrasound waves.

Parallel to the development of acoustic biosensors, we develop ultrasound imaging methods dedicated to the detection of acoustic biomolecules in living organisms. To that end, we elaborate a general nonlinear imaging framework based on the cross-propagation of ultrasound plane waves.

Functional ultrasound imaging (fUS) is a recent neurotechnology capable of recording neural activity via local changes in cerebral blood flow. Our lab effort in this field consists in improving transcranial fUS imaging quality to ease adoption of this technology which is 10 times more resolved and sensitive than fMRI.

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